Aug 17, 2025 | Healthy Tips
Cervical Cancer
Temitope Adebayo
M.Sc. Industrial Microbiology & Biotechnology | Microbiologist | Research Assistant | Biotech Enthusiast
Introduction
Cervical cancer is a malignant tumour arising from the cells of the cervix — the lower part of the uterus that connects to the vagina. It is one of the most common cancers affecting women worldwide, particularly in low- and middle-income countries. According to global estimates, cervical cancer caused approximately 604,000 new cases and 342,000 deaths in 2020 (WHO, 2022).
Recent years have seen intensified efforts toward elimination. In June 2025, global leaders convened at the second Global Cervical Cancer Elimination Forum in Bali, reaffirming commitments to the WHO’s 90-70-90 targets: 90% HPV vaccination by age 15, 70% screening by ages 35 and 45, and 90% treatment of detected cases. Early detection and prevention are crucial, as the disease is highly preventable and treatable when found in its early stages.
Anatomy and Function of the Cervix
The cervix serves as the gateway between the uterus and vagina. It plays an important role during menstruation, pregnancy, and childbirth. It also produces mucus that changes consistency during the menstrual cycle to either facilitate or block sperm entry.
Causes and Risk Factors
The primary cause of cervical cancer is persistent infection with high-risk types of the human papillomavirus (HPV), especially HPV types 16 and 18, which together account for about 70% of cases (Arbyn et al., 2020). Other risk factors include early onset of sexual activity, multiple sexual partners, smoking, prolonged use of oral contraceptives, a weakened immune system (e.g., HIV infection), and a family history of cervical cancer (CDC, 2023)
Pathophysiology
HPV infects the epithelial cells of the cervix, integrating its DNA into the host genome. This disrupts normal cell cycle control, leading to the production of viral oncoproteins E6 and E7, which inactivate tumour suppressor proteins p53 and Rb. Over time, infected cells may progress from cervical intraepithelial neoplasia (CIN) to invasive carcinoma (Bhatla & Singhal, 2020).
Signs and Symptoms
In its early stages, cervical cancer often produces no noticeable symptoms. As the disease progresses, common signs may include abnormal vaginal bleeding (after intercourse, between periods, or after menopause), foul-smelling vaginal discharge, pelvic pain, and pain during sexual intercourse (WHO, 2022).
Screening and Diagnosis
Routine screening is critical for detecting precancerous changes. Common methods include:
- Pap smear: Detects abnormal cervical cells.
- HPV DNA testing: Identifies high-risk HPV strains.
- Visual inspection with acetic acid (VIA): Used in low-resource settings.
If abnormalities are detected, colposcopy and biopsy are performed for confirmation (Koh et al., 2019).
Staging of Cervical Cancer
The FIGO (International Federation of Gynaecology and Obstetrics) staging system classifies cervical cancer based on tumour size, spread to lymph nodes, and metastasis. Staging helps determine the most appropriate treatment plan (Bhatla & Singhal, 2020).
Treatment Options
- Treatment depends on the stage:
- Early-stage: Surgical removal (conisation, hysterectomy).
- Locally advanced: Radiotherapy with concurrent chemotherapy.
- Advanced stage: Palliative care, targeted therapy, and immunotherapy may be considered (Koh et al., 2019).
Prevention
The most effective preventive measures include:
HPV vaccination: Recommended for girls (and boys) before sexual debut, typically between ages 9 and 14.
Safe sexual practices: Limiting the number of partners and using condoms.
Regular screening: Even vaccinated women should be screened, as vaccines do not cover all HPV strains (WHO, 2022).
Global and Regional Statistics
Cervical cancer remains a major public health issue in sub-Saharan Africa, South-East Asia, and parts of Latin America, where screening programmes are less accessible. The WHO aims to eliminate cervical cancer as a public health problem by achieving 90% HPV vaccination coverage, 70% screening coverage, and 90% treatment for detected disease by 2030 (WHO, 2020).
Challenges in Management
Barriers include limited access to vaccines, screening facilities, and cancer treatment centres in low-resource settings. Cultural beliefs, stigma, and lack of awareness also reduce participation in preventive programmes (Arbyn et al., 2020).
Conclusion
Cervical cancer is both preventable and treatable, yet it continues to claim hundreds of thousands of lives each year. Strengthening HPV vaccination programmes, ensuring regular screening, and improving access to treatment are essential steps toward elimination. Awareness and education remain powerful tools in this fight.
References
1. Arbyn, M., et al. (2020). Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. *The Lancet Global Health*, 8(2), e191–e203.
- Bhatla, N., & Singhal, S. (2020). Primary management of cervical cancer: Society of Gynaecologic Oncology consensus guidelines. *Gynaecologic Oncology*, 157(3), 481–493.
3. CDC. (2023). Cervical Cancer. Retrieved from [https://www.cdc.gov/cancer/cervical](https://www.cdc.gov/cancer/cervical)
4. Koh, W.-J., et al. (2019). Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. *Journal of the National Comprehensive Cancer Network*, 17(1), 64–84.
- WHO. (2020). Global strategy to accelerate the elimination of cervical cancer as a public health problem. World Health Organisation.
6. WHO. (2022). Cervical Cancer Fact Sheet. Retrieved from [https://www.who.int/news-room/fact-sheets/detail/cervical-cancer] (https://www.who.int/news-room/fact-sheets/detail/cervical-cancer)
Aug 1, 2025 | Healthy Moves
As we continue our mission to promote health and wellness at Rays of Hope Support Initiative (ROHSI), we would like to shed light on the critical link between obesity and hypertension. These two conditions are closely intertwined and pose a significant threat to global health.
According to the World Health Organisation (WHO), obesity is a major risk factor for developing hypertension, which in turn increases the risk of cardiovascular disease, stroke, and kidney disease. The statistics are alarming: obesity affects 1 in 8 people worldwide, while hypertension affects over 1.28 billion people, making it the leading cause of death and disability globally.
In Africa, the prevalence of obesity and hypertension is rising at an alarming rate. Nigeria, in particular, is facing a significant challenge in this regard. Studies have shown that the prevalence of obesity and hypertension is increasing among Nigerians, with urban areas being disproportionately affected.
One of the most concerning trends is the rise of obesity and hypertension among young people in Nigeria (where over 30% of Nigerian adults are overweight or obese). This can be attributed to various factors, including:
* Consuming high-calorie foods and drinks low in essential nutrients.
* Sedentary lifestyle and lack of regular exercise.
* Family history and genetic factors can play a role.
* Poverty levels that have made the majority reliant on cheaper, energy-dense, but nutrient-poor foods.
* Many Nigerians are unaware of their blood pressure status until complications arise.
* High costs and inadequate medical facilities prevent early detection and treatment.
Way Out!
- We are encouraging consumption of fruits, vegetables, whole grains, and lean proteins. Limit sugary drinks and processed foods.
- Increase in physical activity like outdoor play, sports, and regular exercise. Our schools should prioritise physical education.
- Making available educational journals/resources and guidance on preparing nutritious meals and fostering active lifestyles in languages that our people can easily read and understand
- Implementation of policies that will restrict the advertising of high-sugar, high-fat, and high-salt foods to younger audiences.
To combat this growing epidemic, we need a multi-faceted approach, and we are suggesting the below steps:
- Our policymakers to develop and rigorously enforce policies that promote healthy food environments (e.g., taxes on sugary drinks, subsidies for healthy foods, clear food labelling).
- Design our cities with accessible green spaces, pedestrian-friendly infrastructure, and safe cycling paths to encourage physical activity.
- Ensure routine screening for obesity and hypertension during primary healthcare visits, with clear referral pathways.
- Allocate adequate resources for research into effective prevention and management strategies and for the implementation of public health programmes.
- Mandate and fund comprehensive health education programmes in schools that include nutrition, physical activity, and the risks of NCDs.
To organisations working in this space, we should:
- Unite our voices to advocate for stronger policies and increased government investment in NCD prevention and control. Share data and success stories to build a compelling case.
- Develop and launch joint, culturally sensitive awareness campaigns that utilise various media channels (local radio, community events, social media) to educate the public about the dangers of obesity and hypertension.
- Develop standardised, easy-to-understand health education materials that can be disseminated across different communities. This includes practical advice on healthy eating, portion control, the benefits of physical activity, and stress management.
- Organise free or subsidised medical screening camps in underserved communities, providing accessible blood pressure checks, BMI measurements, and basic health consultations as we do at ROHSI. This can also be expanded when in partnership with local healthcare providers.
- Work with pharmaceutical companies and healthcare providers to explore avenues for making essential medications for hypertension management more affordable and accessible. Establish networks to connect individuals with medical professionals where necessary for ongoing care.
- Implement robust follow-up programmes for individuals identified as having high-risk factors or diagnosed with conditions. This could involve community health workers, peer support groups, or regular check-ins to ensure adherence to treatment plans and lifestyle modifications. This sustained engagement is crucial for long-term behaviour change.
The relationship between obesity and hypertension is complex, but by working together, we can make a difference. By working together—individuals, policymakers, and nonprofits—we can curb this epidemic. Let’s work together to create a healthier future for ourselves and future generations! Let’s promote healthier lifestyles, advocate for better policies, and ensure no one is left behind in the fight for a healthier Nigeria.
Join #ROHSI3 in this mission! Together, we can save lives.
Jul 2, 2025 | News
On Saturday, June 21, 2025, the Rays of Hope Support Initiative (ROHSI) successfully conducted a free medical outreach at Otun Abese Community, Ibadan, Oyo State. Approximately 200 residents, comprising men, women, children, and the elderly, accessed essential healthcare services.
The outreach promoted health awareness, offered medical screenings, provided free medication, and educated the community on healthy living practices. The ROHSI approach focused on proactive health management and accessible care.
At the medical outreach, we provided health education where vital information on maintaining good health, regular medical screenings, and adopting healthy lifestyles were discussed with the participants
Also, there was medical screening to identify various health conditions early, especially on hypertension and diabetes, the two silent killers
Participants also received free medications courtesy of our sponsors and partners. On that day also some individuals that requires further medical attention were referred to appropriate healthcare facilities
Names of individuals with critical medical conditions were listed out for further support and follow-up through our WhatsApp community, where we shared daily health tips and other health opportunities
We extend our deepest gratitude to our sponsors: Codix Pharma Nigeria, Kemisola Bolarinwa through Next Wear Technologies, Africa Social Enterprise Workshop (ASEW) for supporting our social enterprise scheme and other anonymous contributors.
To our host community, Otun Abese Community, for their warmth and hospitality, and our Board of Trustees, Management Team, Staff, and Volunteers for their dedication and hard work. To our family, friends, and ROHSI Community, we say thank you all for your support and generosity. We enjoy always
Major highlights of the outreach:
- A majority of residents are unaware of their health status, highlighting a critical need for increased health awareness campaigns.
- Even those aware of their conditions cannot access necessary care due to the escalating cost of medical services.
- There is an alarming surge in non-communicable diseases (NCDs), particularly hypertension and diabetes. This trend demands urgent attention from the government and other stakeholders.
- The preventable nature of many NCDs, which are tragically claiming the lives of our working and productive adults, is a significant concern that requires immediate and concerted efforts.
The surge in preventable #NCDs demands urgent intervention from government and stakeholders. We urge:
- The implementation of practical healthcare policies (beyond paperwork).
- Introduction of affordable indigenous health insurance schemes for underserved community
- More partnerships from governments, policymakers and organisations of like minds to expand medical outreach programmes.
We reiterate our profound gratitude to all our sponsors, partners, board, and team members for making this outreach a success. We remain committed to bridging healthcare gaps and working towards accessible quality healthcare for all.
Thank you for your unwavering support.
ROHSI Management Team.
May 31, 2025 | Healthy Tips
Every year on May 31, the world observes World No Tobacco Day (WNTD), a global initiative led by the World Health Organisation (WHO) to raise awareness about the dangers of tobacco use and advocate for stronger policies to reduce its consumption. This year’s theme, “Unmasking the Appeal”, focuses on the deceptive strategies employed by the tobacco and nicotine industries to attract new users, particularly young people.
As a leading non-communicable diseases (NCDs) support organisation based in Ibadan, Oyo State, Nigeria, Rays of Hope Support Initiative (ROHSI) stands with the global community in amplifying the call for tobacco control, public health protection, and policy enforcement.
The global tobacco epidemic is a formidable threat, claiming over 8 million lives annually worldwide. Of these, more than 7 million deaths are a direct result of tobacco use, while an alarming 1.3 million deaths are due to non-smokers being exposed to second-hand smoke. This exposure is a critical concern for ROHSI, as it also significantly increases the risk of NCDs in non-smokers.
In Nigeria, the situation is alarming:
- 3.4 million Nigerians (2.9% of adults aged 15+) smoke tobacco (2022 data).
- Male smokers (5.4%) far outnumber female smokers (0.4%).
- Tobacco-related diseases – cancer, heart disease, respiratory illnesses, and stroke – place a heavy burden on Nigeria’s healthcare system.
- Economic losses from tobacco-related illnesses and productivity decline further strain families and the nation.
While reports, such as one from the Tribune newspaper, suggest higher smoking prevalence in some northern states, ROHSI emphasises that tobacco use and its link to NCDs is a pressing issue across all regions, including Oyo State.
At ROHSI, we see firsthand the devastating impact of tobacco on individuals and families affected by NCDs here in Ibadan and across Nigeria.
This World No Tobacco Day, under the theme ‘Unmasking the appeal’, we urge a united front to expose the tobacco industry’s tactics that endanger our youth and perpetuate the cycle of NCDs. The first and most crucial step towards a healthier life, free from the threat of many NCDs, is to say NO to tobacco.
ROHSI encourages every Nigerian to reflect on the popular calls to action: “Breathe clean, live green. Quit tobacco today.”
The ROHSI team challenges every individual in Ibadan, Oyo State, and throughout Nigeria to consider making this powerful pledge: “Today, I am pledging to quit all forms of tobacco and nicotine, including cigarettes, smokeless tobacco products, heated tobacco products, e-cigarettes, nicotine pouches, shisha, and other harmful products, for my health and the health of my community.”
Join us in educating others on the dangers of tobacco and industry tactics, support smoke-free policies in workplaces, schools, and public spaces, advocate for stronger tobacco control laws in Nigeria, and help promote cessation programmes through counselling and support.
Together, we can unmask the truth and build a healthier, tobacco-free Nigeria!
About ROHSI:
Rays of Hope Support Initiative (ROHSI) is a Nigerian non-profit organisation based in Ibadan, Oyo State, dedicated to combating non-communicable diseases (NCDs) through awareness, advocacy, and community support programmes.
#NoTobacco #TobaccoFreeGeneration #PublicHealth #WHO_Africa #WorldNoTobaccoDay #ROHSI3 #Nigeria #Africa #Ibadan #NCDs #WHO_Nigeria #WHO_Africa #WHO #TobaccoFree #QuitSmoking #HealthForAll #NNNGO #NCDAlliance #TobaccoFreeNigeria #HealthForAll #FMoH #NPHCDA #NIgerian
May 17, 2025 | News
Every year on May 17, the global health community observes World Hypertension Day to raise awareness about high blood pressure, a stealthy yet deadly condition affecting over one billion people worldwide. The theme for this year (2025), “Measure Your Blood Pressure Accurately, Control It, Live Longer!”, underscores the urgent need for early detection, proper management, and sustained control of hypertension to prevent life-threatening complications.
In low-income countries like Nigeria, hypertension is not just a health issue; it’s a growing epidemic. Often called the “silent killer”, it frequently goes undetected due to a lack of symptoms until severe damage occurs, leading to #stroke, #heartfailure, #kidneydisease, and premature death. Limited healthcare access, low awareness, high treatment costs, and shortages of medical personnel worsen the crisis, disproportionately affecting vulnerable populations who lack resources for preventive care.
Nigeria’s struggle with #hypertension reflects broader challenges in low-resource settings:
- Many #Nigerians remain unaware of their condition until complications arise.
- High medication costs and weak healthcare infrastructure hinder effective management.
- Unhealthy diets (high in salt), physical inactivity, tobacco use, and stress contribute to rising cases.
Without urgent intervention, #hypertension will continue to strain already fragile health systems, increasing preventable deaths from cardiovascular diseases.
Like other #NGOs working within the health space, #ROHSI3 is making a tangible difference by combating hypertension at the grassroots through:
Community Screenings! Providing free #bloodpressure checks to detect undiagnosed cases.
Awareness Campaigns! Educating communities on risks, prevention, and management.
* Health Education! Promoting low-salt diets, regular exercise, stress management, and smoking/alcohol cessation.
Affordable Medication Access! Ensuring people with hypertension can obtain low-cost antihypertensive drugs.
Continuity of Care! Collaborating with stakeholders to support long-term management for patients.
Our work demonstrates how local interventions save lives where formal healthcare systems fall short.
Today we are saying, together, we can defeat hypertension! To turn the tide against this silent killer, we need collective effort:
To Government & Policymaker, please:
- We are saying, Integrate hypertension screening into primary healthcare systems.
- Subsidise medications and enforce salt reduction policies (e.g., food labelling regulations).
- Launch nationwide public health campaigns on prevention.
To pharmaceutical companies, please:
- Expand access to low-cost generic medications.
- Partner with NGOs such as ours and governments to improve drug availability in underserved areas.
To International Health Bodies (#WHO, #WorldHypertensionLeague, #NCDAlliance, #WorldHeartFederation, etc.):
- Support training programmes for healthcare workers.
- Fund research and tailored interventions for hypertension in low-income countries.
To Our People: What You Can Do:
* Get screened regularly! Early detection saves lives.
* Adopt a Heart-Healthy Lifestyle! Reduce salt, exercise, quit smoking/alcohol, and manage stress.
* Spread Awareness! Encourage family and friends to monitor their blood pressure.
We are saying together we can put a stop to the surge of hypertension if detected early and controlled effectively. This World Hypertension Day, let’s commit to:
- Measuring our blood pressure accurately
- Controlling it through lifestyle changes and medication
- Living longer by adopting healthier habits
Through community efforts, government action, and global support, we can defeat this silent killer in Nigeria and beyond.
Courtesy: Rays Of Hope Support Initiative (ROHSI) Management Team
#LeadOnNCDs #who_nigeria #codixpharma #ActOnNCDs #rohsicares #Rohsi3 #NPHCDA #NCDs #ibadan #WorldHypertensionDay
